Lipid - Lipid - Cholesterol and its derivatives: Cholesterol may be the most intensely studied small molecule of biological origin. Cholesterol structure. There is no internal plane of symmetry, so every carbon atom is different. These include bile Cholestereol is a hydrophobic (non-polar) compound basically because of its ring structure and the hydrocarbon chain on C-5 ring. Triglycerides: A molecule containing three molecules of fatty acids and one molecule of glycerol (a sugar). Introduction to Cholesterol Metabolism. Cholesterol: A type of fat made by the liver. (Adapted from en.wikipedia.org) Remember that bond-line structures don't show the hydrogen atoms that are attached to carbon. Cholest-5-ene-3beta,25-diol Due to the presence of the hydrophilic hydroxyl group and the hydrophobic hydrocarbon region cholesterol is termed as an amphipatic molecule. At the molecular level, cholesterol possesses a slick and rigid structure. > The structure of cholesterol with its numbering is shown below. There are eight chiral centres in cholesterol. At the molecular level, cholesterol possesses a slick and rigid structure. 25-Hydroxycholesterol. Lipoproteins: A round structure containing cholesterol and triglycerides on the inside, surrounded by a protein coat on the outside. The hydroxyl group (-OH) in cholesterol is aligned with the phosphate head of the phospholipid on the cell membrane, which the rest of the cholesterol goes with the fatty acid of … The only hydrophilic group you have on the molecule is the hydroxyl group on ring 1 Cholesterol is an extremely important biological molecule that has roles in membrane structure as well as being a precursor for the synthesis of the steroid hormones, the bile acids, and vitamin D.Both dietary cholesterol, and that synthesized de novo, are transported through the circulation in lipoprotein particles. 2140-46-7. The molecule is extremely hydrophobic. Each chiral carbon must have four different groups. It is an essential component of cell membranes, and is the precursor for the synthesis of several important molecules. Cholesterol is referred to as an amphipathic molecule, that it contains its hydrophilic and hydrophobic parts. 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